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New hepatocyte model options
April 2019
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WALKERSVILLE, Md.—Last month saw Lonza announce the addition of Verified for Spheroids Human Hepatocytes to its portfolio, a new offering that is pre-screened for the ability to promote rapid spheroid formation in cell culture. These new
primary plateable hepatocytes were debuted at the 58th Society of Toxicology Annual Meeting and ToxExpo in March. Lonza notes that current hepatocyte models face issues of long-term functionality, which 2D hepatocyte cultures often lack, and the ability to form spheroids in culture, which not all hepatocyte donor batches are capable of.
 
“Using spheroids as in-vitro liver model systems requires researchers to carefully select donors and thoroughly examine hepatocyte lots in advance,” commented Erica Chamberlin, technical specialist at Lonza. “With our Verified for Spheroids Human Hepatocytes, we take on this burden on behalf of our customers, enabling them to focus on what matters most—their science.”

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