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A single-cell atlas
May 2020
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A research team led by Prof. Guo Guoji of the Center for Stem Cell and Regenerative Medicine at the Zhejiang University School of Medicine recently analyzed the cell type composition of all major human organs. They used a high-throughput scRNA-seq platform known as Microwell-seq that they had developed, and created a “human cell landscape” (HCL) using the RNA sequences from more than 700,000 single cells. The dataset was grouped into more than 100 major clusters and 800 subtypes, and the team created an HCL website (which can be found at https://db.cngb.org/HCL/) as well as a single-cell HCL analysis pipeline to identify cells.
Guo commented in part that “A perfect human cell atlas calls for integration of spatial information, multi-omics data and population analysis, which requires the concerted efforts of the global scientific community.”

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